>>104413642
That's because it is too good to be true. The retard who wrote it is using substitutes that aren't as effective as the real thing like
>not using valporic acid as HDACi
There's restrictions on that shit because they do cause teratomas. Theoretically, he's correct in reprogramming cells to express more OKSM but he doesn't explain the extent to which he thinks they're being reprogrammed on his regimen because his entire observation is mostly
>bro I feel good after hopping on this new diet
>trust me bro, what works in vitro and in mice is surely capable of working perfectly in a human
>my sample size is a grand total of 1 retard experimenting on himself and patting himself on the back
There's a shit ton of moving parts in vitro in tissue culture. It's easy enough to make them overexpress OKSM. But it becomes exponentially harder and riskier to do that in complex systems like a human.
Even if he did succeed in reprogramming his epigenetic state, he gave fuck all information on what sites he did reprogram because he's another """biohacker""" with fuckall who hasn't done shit like CHiP-seq or ATAC-seq. I guarantee you if he did, he wouldn't post it on /sci/ of all places because the results of that research is enough to fill a good paper.
TLDR; there's a lot more moving parts to reprogramming your epigenetic memory than just one drug like apigenin or a single cocktail/regimen. Even if you did, you wouldn't know the right dose because nobody really knows the right dose and cocktail for mice, let alone men
>t. MSc Biotech who spent more than a year into making a proposal for reprogramming

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